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Erectile Dysfunction Treatments and Medicine Use 治療勃起功能障礙藥物使用說明

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Erectile Dysfunction Treatments and Medicine Use 治療勃起功能障礙藥物使用說明

2024/1/29
 
Viagra
Spedra
Cialis
Peak drug concentration time
48-60 minutes
30-45 minutes
120 minutes
Drug half-life**
2.6-3.7hours
5*-17 hours
17.5 hours
Suggested initial dosage
50mg
100mg
10mg
Medication price
100mg/NTD450 (50mg/NTD399)
200mg/NTD350
20mg/NTD500
Contraindications
  • Allergic to this medication
  • Taking nitrate medications
  • Cardiovascular risk factors unsuitable for sexual activity
  • Severe liver or kidney dysfunction
  • Blood pressure below 90/50 mmHg or above 170/100 mmHg
  • History of stroke or myocardial infarction within the past 6 months
  • Hereditary degenerative retinal disorders
  • Patients with one eye blinded due to non-arteritic anterior ischemic optic neuropathy
  • Previously experienced prolonged penile erection
  • Allergic to this medication
  • Taking nitrate medications
  • Cardiovascular risk factors unsuitable for sexual activity
  • Severe liver or kidney dysfunction
  • Blood pressure below 90/50 mmHg or above 170/100 mmHg
  • History of stroke, myocardial infarction, or life-threatening arrhythmia within the past 6 months
  • Hereditary degenerative retinal disorders
  • Patients with one eye blinded due to non-arteritic anterior ischemic optic neuropathy
  • Previously experienced prolonged penile erection
  • Allergic to this medication
  • Taking nitrate medications
  • Cardiovascular risk factors unsuitable for sexual activity
  • Severe liver or kidney dysfunction
  • Blood pressure below 90/50 mmHg or above 170/100 mmHg
  • History of stroke or myocardial infarction within the past 6 months
  • Patients with one eye blinded due to non-arteritic anterior ischemic optic neuropathy
  • Previously experienced prolonged penile erection
Side effects
Headache, facial flushing, gastrointestinal discomfort, visual abnormalities, diarrhea, dizziness, skin rash
Headache, facial flushing, nasal congestion, sinus congestion, back pain, muscle soreness
Headache, facial flushing, gastrointestinal discomfort, dizziness, nasal congestion, muscle soreness
Method of use
Take orally 30-60 minutes before sexual activity; the medication requires sexual stimulation to work.
Take orally 15-30 minutes before sexual activity; the medication requires sexual stimulation to work.
Take orally 2 hours before sexual activity; the medication requires sexual stimulation to work.
Characters
  • On the market for a longer time.
  • When used in combination with medications for benign prostatic hyperplasia (alpha-adrenergic blockers), be cautious of low blood pressure. For initial combination use, start with the minimum dosage.
  • Faster onset of action.
  • Suitable for patients with erectile dysfunction caused by diabetes.
  • When used in combination with medications for benign prostatic hyperplasia (alpha-adrenergic blockers), be cautious of low blood pressure. For initial combination use, start with the minimum dosage.
  • Longer duration of action, lasting 24-36 hours.
  • Animal studies found that long-term daily use can reduce sperm production in some dogs, but this phenomenon has not been observed in humans.
  • When used in combination with medications for benign prostatic hyperplasia (alpha-adrenergic blockers), be cautious of low blood pressure. For initial combination use, start with the minimum dosage.

* Half-life as recorded in the domestic drug monograph.

** The suggested initial dosage is the starting dose recommended by the pharmaceutical company.

Precautions

  • If an erection lasts longer than 4 hours after taking the medication, seek medical attention immediately.
  • Currently, there are no reports of these three medications being used together, and it is not recommended to use them simultaneously.
  • Using these three medications will not increase libido, Taking the medication without sexual stimulation will not result in an erection.
  • If you experience any discomfort after taking the medication, inform your doctor.

There are currently three approved medications available for treating erectile dysfunction in the domestic market: Viagra (Sildenafil), Spedra (Avanafil), and Cialis (Tadalafil). According to the results of clinical trials, the mechanism of action of these three drugs is to promote the relaxation of penile smooth muscle, leading to full of penile blood and erection. As for clinical efficacy, there is currently no evidence to suggest which medication is more effective. All three medications cause vasodilation and may have an additive effect with nitrate medications commonly used by patients with cardiovascular disease, potentially leading to dangerously low blood pressure. Therefore, patients with unstable coronary artery disease and those taking nitrate medications are not suitable for these three drugs. Additionally, patients with cardiovascular disease should use them with caution and consult a doctor for evaluation before use.

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